Thomas, 147 patient curcumin long COVID RCT: 44% better improvement [p=0.02] https://c19p.org/thomas3
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A Randomised, Double-Blind, Placebo-Controlled Trial Evaluating Concentrated Phytochemical-Rich Nutritional Capsule in Addition to a Probiotic Capsule on Clinical Outcomes among Individuals with COVID-19—The UK Phyto-V Study
et al., COVID, doi:10.3390/covid2040031
RCT 147 long COVID patients in the UK, 56 treated with a phytochemical-rich concentrated food capsule, showing improved recovery with treatment. Treatment included curcumin, bioflavonoids, chamomile, ellagic acid, and resveratrol.
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relative improvement, 44.3% better, RR 0.56, p = 0.02, treatment mean 6.1 (±7.5) n=74, control mean 3.4 (±6.1) n=73, CFS.
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relative improvement, 81.8% better, RR 0.18, p < 0.001, treatment mean 6.6 (±10.5) n=74, control mean 1.2 (±7.4) n=73, SWS.
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relative improvement, 63.6% better, RR 0.36, p = 0.02, treatment mean 1.1 (±2.0) n=74, control mean 0.4 (±1.5) n=73, CSS.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Thomas et al., 3/22/2022, Double Blind Randomized Controlled Trial, placebo-controlled, United Kingdom, Europe, peer-reviewed, 7 authors, study period May 2020 - May 2021, this trial uses multiple treatments in the treatment arm (combined with bioflavonoids, chamomile, ellagic acid, resveratrol) - results of individual treatments may vary, Phyto-V trial.
Contact:
robert.thomas@bedfordhospital.nhs.uk (corresponding author), madeleine.williams@bedfordhospital.nhs.uk, yuuki.yanagisawa@bedfordhospital.nhs.uk, rajeev.kumar@bedordhospital.nhs.uk, jeffrey.aldous@beds.ac.uk, angel.chater@beds.ac.uk, rf451@cam.ac.uk.
Late treatment
is less effective
is less effective
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